DAS-28 with ESR (Rheumatoid Arthritis)
Measures rheumatoid arthritis activity with 28 joints, ESR and global assessment.
When to use
Adults with rheumatoid arthritis to measure activity and track treatment response.
Pearls and pitfalls
- DAS-28 uses 28 tender and swollen joints, ESR and a 100 mm global assessment.
- The formula uses the square root of the counts and the logarithm of ESR.
- Remission is defined below 2.6; high activity above 5.1.
- The score depends on accurate joint counts and should be performed by the same observer when possible.
Fill in the fields to see the result.
Formula
DAS28-ESR = 0.56 × √tender joints + 0.28 × √swollen joints + 0.70 × ln(ESR) + 0.014 × global assessment.
Evidence
Disease activity index derived and validated in rheumatoid arthritis, with remission and activity cutoffs.
References
- Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Arthritis Rheum. 1995;38(1):44-48. doi:10.1002/art.1780380107
Frequently asked questions
What is DAS-28 with ESR (Rheumatoid Arthritis)?
Measures rheumatoid arthritis activity with 28 joints, ESR and global assessment. Adults with rheumatoid arthritis to measure activity and track treatment response.
How is the result calculated?
DAS28-ESR = 0.56 × √tender joints + 0.28 × √swollen joints + 0.70 × ln(ESR) + 0.014 × global assessment.
How should the result be interpreted?
Disease activity index derived and validated in rheumatoid arthritis, with remission and activity cutoffs.
What are the sources?
Prevoo ML, van 't Hof MA, Kuper HH, van Leeuwen MA, van de Putte LB, van Riel PL. Modified disease activity scores that include twenty-eight-joint counts. Arthritis Rheum. 1995;38(1):44-48.