Sepsis-Induced Coagulopathy Score
Identifies sepsis-induced coagulopathy using platelets, INR and SOFA.
When to use
Patients with sepsis in intensive care, to recognize associated coagulopathy and guide monitoring.
Pearls and pitfalls
- Platelets below 150,000/µL and INR above 1.2 start to score.
- A SOFA of 2 or more adds 1 point.
- Four points or more define SIC in the proposed criterion.
- The score does not replace assessment of bleeding, thrombosis and the cause of coagulopathy.
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Formula
Add platelets (0 to 2), INR (0 to 2) and SOFA (0 to 2); total from 0 to 6, requiring at least 2 points from platelets and INR.
Evidence
Criterion proposed for sepsis-induced coagulopathy, with a cutoff of 4 for diagnosis.
References
- Iba T, Nisio MD, Levy JH, Kitamura N, Thachil J. New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey. BMJ Open. 2017;7(9):e017046. doi:10.1136/bmjopen-2017-017046
Frequently asked questions
What is Sepsis-Induced Coagulopathy Score?
Identifies sepsis-induced coagulopathy using platelets, INR and SOFA. Patients with sepsis in intensive care, to recognize associated coagulopathy and guide monitoring.
How is the result calculated?
Add platelets (0 to 2), INR (0 to 2) and SOFA (0 to 2); total from 0 to 6, requiring at least 2 points from platelets and INR.
How should the result be interpreted?
Criterion proposed for sepsis-induced coagulopathy, with a cutoff of 4 for diagnosis.
What are the sources?
Iba T, Nisio MD, Levy JH, Kitamura N, Thachil J. New criteria for sepsis-induced coagulopathy (SIC) following the revised sepsis definition: a retrospective analysis of a nationwide survey. BMJ Open. 2017;7(9):e017046.