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Rochester Criteria for Febrile Infants

Identifies febrile infants at low risk of serious bacterial infection.

When to use

Febrile infants up to 60 days, as support for serious bacterial infection risk assessment.

Pearls and pitfalls
  • The criteria include age, previous health, skin examination, blood count, urine and stool.
  • All criteria must be present to classify low risk.
  • Age and clinical appearance remain central; the score does not replace infant assessment.
  • Management varies with local protocols and should consider access to follow-up.

Age above 28 days

Well appearing

Previously healthy

No skin, soft tissue or bone infection

White cells between 5,000 and 15,000/µL

Band count up to 1,500/µL

Urine with up to 10 white cells per high power field

Stool with up to 5 white cells per high power field, if diarrhea

0/8 low risk criteria

Low risk criteria not all met

Consider full investigation and admission according to age and clinical picture.

Formula

Count how many of the eight low risk criteria are present; eight of eight defines low risk.

Evidence

Criteria evaluated in a cohort of febrile infants to identify low risk of serious bacterial infection.

References

  1. Jaskiewicz JA, McCarthy CA, Richardson AC, et al. Febrile infants at low risk for serious bacterial infection: an appraisal of the Rochester criteria and implications for management. Pediatrics. 1994;93(6 Pt 1):983-987. https://pubmed.ncbi.nlm.nih.gov/8065869/

Frequently asked questions

What is Rochester Criteria for Febrile Infants?

Identifies febrile infants at low risk of serious bacterial infection. Febrile infants up to 60 days, as support for serious bacterial infection risk assessment.

How is the result calculated?

Count how many of the eight low risk criteria are present; eight of eight defines low risk.

How should the result be interpreted?

Criteria evaluated in a cohort of febrile infants to identify low risk of serious bacterial infection.

What are the sources?

Jaskiewicz JA, McCarthy CA, Richardson AC, et al. Febrile infants at low risk for serious bacterial infection: an appraisal of the Rochester criteria and implications for management. Pediatrics. 1994;93(6 Pt 1):983-987.

Updated