Ganzoni Total Iron Deficit
Estimates total iron needed to correct anemia and replenish stores.
When to use
Planning iron replacement in adults with iron deficiency anemia and estimated blood loss.
Pearls and pitfalls
- The formula adds iron to raise hemoglobin to target and the desired iron store.
- When weight is below 35 kg, the standard store is calculated as 15 mg/kg.
- The result is an estimate; the administered dose depends on formulation, route and tolerance.
- The target hemoglobin should be set individually and must not exceed the institution safe limit.
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Formula
Total iron (mg) = weight (kg) × (target hemoglobin minus current hemoglobin) × 2.4 + iron stores (mg).
Evidence
Ganzoni formula for total iron deficit, used to plan parenteral replacement.
References
- Ganzoni AM. [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr. 1970;100(8):301-303. https://pubmed.ncbi.nlm.nih.gov/5413912/
Frequently asked questions
What is Ganzoni Total Iron Deficit?
Estimates total iron needed to correct anemia and replenish stores. Planning iron replacement in adults with iron deficiency anemia and estimated blood loss.
How is the result calculated?
Total iron (mg) = weight (kg) × (target hemoglobin minus current hemoglobin) × 2.4 + iron stores (mg).
How should the result be interpreted?
Ganzoni formula for total iron deficit, used to plan parenteral replacement.
What are the sources?
Ganzoni AM. [Intravenous iron-dextran: therapeutic and experimental possibilities]. Schweiz Med Wochenschr. 1970;100(8):301-303.