Estimated Blood Volume
Estimates total blood volume from height, weight and sex.
When to use
Blood volume estimate to plan massive transfusion or calculate allowable loss in adults.
Pearls and pitfalls
- The Nadler equation uses height in meters and weight in kg, with different coefficients by sex.
- Obesity, pregnancy and extremes of lean mass change the estimate.
- Estimated volume does not replace clinical response or measured losses in active bleeding.
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Formula
Men: 0.3669 × height³ + 0.03219 × weight + 0.6041. Women: 0.3561 × height³ + 0.03308 × weight + 0.1833, with height in meters.
Evidence
Equation derived in normal adults to predict blood volume from anthropometric measurements.
References
- Nadler SB, Hidalgo JH, Bloch T. Prediction of blood volume in normal human adults. Surgery. 1962;51(2):224-232. https://pubmed.ncbi.nlm.nih.gov/21936146/
Frequently asked questions
What is Estimated Blood Volume?
Estimates total blood volume from height, weight and sex. Blood volume estimate to plan massive transfusion or calculate allowable loss in adults.
How is the result calculated?
Men: 0.3669 × height³ + 0.03219 × weight + 0.6041. Women: 0.3561 × height³ + 0.03308 × weight + 0.1833, with height in meters.
How should the result be interpreted?
Equation derived in normal adults to predict blood volume from anthropometric measurements.
What are the sources?
Nadler SB, Hidalgo JH, Bloch T. Prediction of blood volume in normal human adults. Surgery. 1962;51(2):224-232.