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CHADS2 Score

Estimates stroke risk in nonvalvular atrial fibrillation.

When to use

Historical thromboembolic risk stratification in adults with nonvalvular atrial fibrillation.

Pearls and pitfalls
  • One point for heart failure, hypertension, age 75 or older and diabetes; two points for prior stroke or TIA.
  • CHA2DS2-VASc and CHA2DS2-VA include additional factors and are preferred in current guidelines.
  • The anticoagulation decision considers bleeding risk, kidney function, adherence and patient preference.

Congestive heart failure

Hypertension

Age 75 years or older

Diabetes mellitus

Previous stroke or transient ischemic attack

0/6 points

Low risk

The score does not decide anticoagulation alone; integrate bleeding risk, preferences and the current guideline.

Formula

Sum the five factors, weighting prior stroke or TIA as 2; result from 0 to 6.

Evidence

Scheme combined and validated in the National Registry of Atrial Fibrillation, with annual stroke risk rising with the score.

References

  1. Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285(22):2864-2870. doi:10.1001/jama.285.22.2864

Frequently asked questions

What is CHADS2 Score?

Estimates stroke risk in nonvalvular atrial fibrillation. Historical thromboembolic risk stratification in adults with nonvalvular atrial fibrillation.

How is the result calculated?

Sum the five factors, weighting prior stroke or TIA as 2; result from 0 to 6.

How should the result be interpreted?

Scheme combined and validated in the National Registry of Atrial Fibrillation, with annual stroke risk rising with the score.

What are the sources?

Gage BF, Waterman AD, Shannon W, Boechler M, Rich MW, Radford MJ. Validation of clinical classification schemes for predicting stroke: results from the National Registry of Atrial Fibrillation. JAMA. 2001;285(22):2864-2870.

Updated