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Candida Score

Estimates the risk of invasive candidiasis in critically ill patients colonized by Candida.

When to use

Nonneutropenic critically ill patients with Candida colonization, to support the decision for investigation or early treatment.

Pearls and pitfalls
  • Parenteral nutrition, surgery and multifocal colonization score 1 point each; severe sepsis scores 2.
  • The cutoff of 3 was associated with a higher probability of invasive candidiasis in the original study.
  • Colonization is not infection; the score supports the decision and does not confirm the diagnosis.
  • Local epidemiology and prior antifungal use modify score performance.

Total parenteral nutrition

Surgery

Multifocal Candida colonization

Severe sepsis

0/5 points

Low risk (less than 3)

Keep clinical surveillance and reassess if new risk factors appear.

Formula

Add 1 point for parenteral nutrition, surgery and multifocal colonization; 2 points for severe sepsis.

Evidence

Score derived in a multicenter study of colonized critically ill patients, with a cutoff of 3 for invasive candidiasis.

References

  1. Leon C, Ruiz-Santana S, Saavedra P, et al. A bedside scoring system (Candida score) for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization. Crit Care Med. 2006;34(3):730-737. doi:10.1097/01.ccm.0000202208.37364.7d

Frequently asked questions

What is Candida Score?

Estimates the risk of invasive candidiasis in critically ill patients colonized by Candida. Nonneutropenic critically ill patients with Candida colonization, to support the decision for investigation or early treatment.

How is the result calculated?

Add 1 point for parenteral nutrition, surgery and multifocal colonization; 2 points for severe sepsis.

How should the result be interpreted?

Score derived in a multicenter study of colonized critically ill patients, with a cutoff of 3 for invasive candidiasis.

What are the sources?

Leon C, Ruiz-Santana S, Saavedra P, et al. A bedside scoring system (Candida score) for early antifungal treatment in nonneutropenic critically ill patients with Candida colonization. Crit Care Med. 2006;34(3):730-737.

Updated